2023
An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis
S. Krishnananthasivam, H. Li, R. Bouzeyen, B. Shunmuganathan, K. Purushotorman, X. Liao, F. Du, C. Guldager Kring Friis, F. Crawshay-Williams, L. H. Boon, Q. Xinlei, C. En Zuo Chan, R. Sobota, M. Kozma, V. Barcelli Jo, G. Wang, H. Huang, A. Floto, P. Bifani, B. Javid & P. A. MacAry. npj Vaccines. 2023.
Navigating a Path to Rifampicin Resistance in Tuberculosis
Agarwal S, and Javid B. mBio. 2023.
2022
Therapeutic Vaccines for Tuberculosis: An Overview
Bouzeyen R, and Javid B. Frontiers in Immunology. 2022.
2021
Harnessing Twitter data to survey public attention and attitudes towards COVID-19 vaccines in the UK
Fazel S, Zhang L, Javid B, Brikell I, and Chang Z. Scientific Reports. 2021
100 years of antibody solitude in TB
Divangahi M, Javid B, Kaufmann E. Nature Immunology. 2021
Clinically Relevant Mutations of Mycobacterial GatCAB Inform Regulation of Translational Fidelity.
Li YY, Cai RJ, Yang JY, Hendrickson TL, Xiang Y, Javid B. mBio. 2021.
Should masks be worn outdoors?
Javid B, Bassler D, Bryant MB, Cevik M, Tufekci Z, Baral S. The British Medical Journal. 2021.
Direct and indirect evidence of efficacy and safety of rapid exercise tests for exertional desaturation in Covid-19: a rapid systematic review.
Kalin A, Javid B, Knight M, Inada-Kim M, Greenhalgh T. Systematic Reviews. 2021.
Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis.
Watson A, Li H, Ma B, Weiss R, Bendayan D, Abramovitz L, Ben-Shalom N, Mor M, Pinko E, Bar Oz M, Wang Z, Du F, Lu Y, Rybniker J, Dahan R, Huang H, Barkan D, Xiang Y, Javid B, Freund NT. Nature Communications. 2021.
Most-Probable-Number-Based Minimum Duration of Killing Assay for Determining the Spectrum of Rifampicin Susceptibility in Clinical Mycobacterium tuberculosis Isolates.
Vijay S, Nhung HN, Bao NLH, Thu DDA, Trieu LPT, Phu NH, Thwaites GE, Javid B, Thuong NTT. Antimicrobial Agents and Chemotherapy. 2021.
2020
Managing outbreaks of highly contagious diseases in prisons: a systematic review
Beaudry G, Zhong S, Whiting D, Javid B, Frater J, Fazel S. BMJ Global Health. 2020.
Forward Genetics Reveals a gatC-gatA Fusion Polypeptide Causes Mistranslation and Rifampicin Tolerance in Mycobacterium smegmatis
Cai RJ, Su HW, Li YY, Javid B. Frontiers in Immunology. 2020.
Selective translation by alternative bacterial ribosomes
Chen YX, Xu ZY, Ge X, Sanyal S, Lu ZJ, Javid B. PNAS. 2020.
Premature termination codon readthrough in Drosophila varies in a developmental and tissue-specific manner
Chen Y, Sun T, Bi Z, Ni JQ, Pastor-Pareja JC, Javid B. Scientific Reports. 2020.
Clinically relevant mutations in mycobacterial LepA cause rifampicin-specific phenotypic resistance
Wang BW, Zhu JH, Javid B. Scientific Reports. 2020
Covid-19: should the public wear face masks?
Javid B, Weekes MP, Matheson NJ. The British Medical Journal. 2020.
2019
HspX promotes the polar localization of mycobacterial protein aggregates
Zhang YW, Zhu JH, Wang ZQ, Wu Y, Meng X, Zheng X, Javid B. Scientific Reports. 2019
Measurement of specific mycobacterial mistranslation rates with gain-of-function reporter systems
Yu-Xiang Chen, Miaomiao Pan, Yue-Meng Chen and Babak Javid. Journal of Visual Experiments. 2019
Derivatives of natural product agrimophol as disruptors of intrabacterial pH homeostasis in Mycobacterium tuberculosis
Jie Wu, Ran Mu,….., Carl F. Nathan, Babak Javid. ACS Infectious Disease. 2019
2018
Transmission of toxigenic Corynebacterium diphtherae by a fully immunised resident returning from a visit to West Africa, United Kingdom, 2017
David Edwards, Dianne Kent,...Babak Javid,...David Litt, Mark Reacher. EuroSurvallience. 2018
Kasugamycin potentiates rifampicin and limits emergence of resistance in Mycobacterium tuberculosis by specifically decreasing mycobacterial mistranslation
Swarnava Chaudhuri, Liping Li, Matthew Zimmerman, Yuemeng Chen, Yu-Xiang Chen, Melody N. Toosky, Michelle Gardner, Miaomiao Pan, Yang-Yang Li, Qingwen Kawaji, Jun-Hao Zhu, Hong-Wei Su, Amanda J. Martinot, Eric J. Rubin, Veronique Dartois* and Babak Javid*. eLife. 2018.
Rifampicin can induce antibiotic tolerance in mycobacteria via paradoxical changes in rpoB transcription
Jun-Hao Zhu, Biwei Wang, Miaomiao Pan, Yu-Na Zeng, Hesper Rego and Babak Javid. Nature Communications. 2018.
More than merely drug resistance
Chen YX, Javid B. Nature Microbiology. 2018
Antibodies and tuberculosis: finally coming of age?
Li H, Javid B. Nature Reviews Immunology. 2018.
2017
Latently and uninfected healthcare workers exposed to tuberculosis make protective antibodies against Mycobacterium tuberculosis
Hao Li, Xing-xing Wang, Bin Wang, Lei Fu, Guan Liu, Yu Lu, Min Cao, Hairong Huang* and Babak Javid*. PNAS. 2017
2016
DfrA-ThyA double-deletion in para-aminosalicylic acid resistant Mycobacterium tuberculosis Beijing strains
Danesh Moradigaravand, Louis Grandjean, Elena Martinez, Hao Li, Jun Zheng, Jorge Coronel, David Moore, M. Estee Torok, Vitali Sintchenko, Hairong Huang, Babak Javid, Julian Parkhill, Sharon J. Peacock and Claudio U Koser. Antimicrobial Agents and Chemotherapy. 2016.
Plasma membrane profiling reveals upregulation of ABCA1 by infected macrophages leading to restriction of mycobacterial growth
Jing Long, Robindra Basu Roy, Yanjia J Zhang, Robin Antrobus, Yuxian Du, Duncan L Smith, Michael P Weekes and Babak Javid. Frontiers in Microbiology. 2016
Over-expression of the mycobacterial trehalose-phosphate phosphatase OtsB2 results in a defect in macrophage phagocytosis associated with increased macrophage-mycobacterial adhesion
Hao Li, Mei Wu, Yan Shi and Babak Javid. Frontiers in Microbiology. 2016.
The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity
Hong-Wei Su, Jun-Hao Zhu, Hao Li, Rong-Jun Cai, Christopher Ealand, Xun Wang, Yu-Xiang Chen, Masood ur Rehman Kayani, Ting F. Zhu, Danesh Moradigaravand, Hairong Huang, Bavesh D. Kana and Babak Javid. Nature Microbiology. 2016.
Whole-genome sequencing for the diagnosis of drug-resistant tuberculosis
Javid B, Török ME. Lancet Infectious Disease. 2016.
2015
Transmitted extended-spectrum extensively drug-resistant tuberculosis in Beijing, China, with discordant whole-genome sequencing analysis results
Hao Li, Masood ur Rehman Kayani, Yunting Gu, Xiabo Wang, Ting Zhu, Hongfei Duan, Yifeng Ma, Hairong Huang* and Babak Javid*. The Journal of Clinical Microbiology. 2015.
Uniform and amorphous rifampicin microspheres obtained by freezing induced LLPS during lyophilisation
Chun Liu, Chao Kong, Guoliang Wu, Junhao Zhu, Babak Javid, Feng Qian. International Journal of Pharmaceutics. 2015.
Translational misreading in Mycobacterium smegmatis increases in stationary phase
Tianqi Leng, Miaomiao Pan, Xu Xin and Babak Javid. Tuberculosis. 2015.
Tuberculosis: hey there, lonely guy!
Zhu JH, Javid B. Molecular Cell. 2015
Drug-resistance mechanisms and tuberculosis drugs
Köser CU, Javid B, Liddell K, Ellington MJ, Feuerriegel S, Niemann S, Brown NM, Burman WJ, Abubakar I, Ismail NA, Moore D, Peacock SJ, Török ME. Lancet. 2015.
2014
Prevalence and drug-resistance of non-tuberculous mycobacteria in Northern China, 2008-2011
Xiabo Wang, Hao Li, Guanglu Jiang, Liping Zhao, Yifeng Mao, Babak Javid and Hairong Huang. Emerging Infectious Disease. 2014.
Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance
Babak Javid, Flavia Sorrentino, Melody Toosky, Wen Zheng, Jessica T Pinkham, Nina Jain, Miaomiao Pan, Padraig Deighan and Eric J Rubin. PNAS. 2014.
Protein mistranslation: friend or foe?
Ribas de Pouplana L, Santos MA, Zhu JH, Farabaugh PJ, Javid B. Trends in Biochemical Sciences. 2014.
Novel diagnostics and therapeutics for drug-resistant tuberculosis
Toosky M, Javid B. British Medical Bulletin. 2014.
2013
Functional Role of Methylation of G518 of the 16S rRNA 530 loop by GidB in Mycobacterium tuberculosis
Sharon Y Wong, Babak Javid, Balahsubrahmanyam Adepalli, Grzegorz Piszczek, Michael B Strader, Patrick A Limbach, Clifton E Barry III. Antimicrobial Agents and Chemotherapy. 2013
2012
MmpL3 is the cellular target of the antitubercular pyrrole derivate BM212
Valentina La Rosa, Giovanna Poce, Julio Ortiz Canseco, Silvia Buroni, Maria Rosalia Pasca, Mariangela Biava, Ravikiran M. Raju, Giulio Cesare Porretta, Salvatore Alfonso, Claudio Battilocchio, Babak Javid, Flavia Sorrentino, Thomas Ioerger, James Sacchettini, Fabrizio Manetti, Maurizio Botta, Alessandro De Logu, Eric Rubin, and Edda De Rossi. Antimicrobial Agents and Chemotherapy. 2012.
2011
Nanotubes: shaking hands, talking, or sharing?
Javid B, Derbyshire KM. Frontiers in Microbiology. 2011.
2008
A 58-year-old woman with abdominal symptoms and elevated C-reactive protein
Marie-Louise Daly, David J Cartwright, Paul J Lehner and Babak Javid. PLOS Medicine. 2008.
Human H+ATPase a4 subunit mutations causing renal tubular acidosis reveal a role for interaction with phosphofructokinase-1
Ya Su, Katherine G Blake-Palmer, Sarah Sorrel, Babak Javid, Katherine Bowers, Aiwu Zhou, Simon H Chang, Seema Qamar, and Fiona E Karet. American Journal of Physiology - Renal Physiology. 2008.
2007
Schistosomal colonic polyposis in an HIV-positive man
Babak Javid, Sani H Aliyu, Vicki E Save, Andrew J Carmichael and Andrew M Lever. AIDS. 2007.
Post-partum associated septic arthritis due to Mycoplasma hominis
Chia-Ling Phuah, Babak Javid, Sani H Aliyu and Andrew M Lever. Journal of Infection. 2007.
Structure and function: heat shock proteins and adaptive immunity
Javid B, MacAry PA, Lehner PJ. The Journal of Immunology. 2007
2004
Molecular studies of anti-HLA-A2 using light chain shuffling: a structural model for HLA antibody binding
Nicholas A. Watkins, Timothy R. Dafforn, Marijke Kuijpers, Colin Brown, Babak Javid, Paul J Lehner, Cristina Navarrete and Willem H. Ouwehand. Tissue Antigens. 2004.
Peptides complexed to HSP70 generate efficient human CTL responses
Babak Javid†, Paul A MacAry†, Wulf Oehlmann, Mahavir Singh and Paul J Lehner. Biochemical Society Interactions. 2004.
HSP70 Peptide-Binding Mutants Separate Antigen Delivery From Dendritic Cell Stimulation
Paul A MacAry†, Babak Javid†, R Andres Floto, Ken G Smith, Wulf Oehlmann, Mahavir Singh and Paul J Lehner. Immunity. 2004.
2002
High rates of tuberculosis in end-stage renal failure: the impact of international migration
David Moore, Liz Lightstone, Babak Javid, and Jon S Friedland. Emerging Infectious Disease. 2002.
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